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| 扫描近场光学显微镜及其在单分子探测中的应用 | |
| 引用本文： | 胡明铅,蔡继业. 扫描近场光学显微镜及其在单分子探测中的应用[J]. 化学进展, 2008, 20(6): 984-988 |
| 作者姓名： | 胡明铅 蔡继业 |
| 作者单位： | 暨南大学生命科学技术学院化学系,广州,510632;暨南大学生命科学技术学院化学系,广州,510632 |
| 基金项目： | 国家自然科学基金 , 国家自然科学基金 |
| 摘 要： | 扫描近场光学显微镜在光学显微镜中具有独特的性能,其突破衍射光限制,具有单分子探测灵敏度,且在研究时不损伤生物样品。文中简要介绍了扫描近场光学显微镜的原理,详述近年来扫描近场光学显微镜在单分子探测中的应用,介绍了扫描近场光学显微镜结合量子点对单分子探测的进展,并对单分子探测的前景做了展望。 |
| 关 键 词： | 扫描近场光学显微镜 单分子探测 量子点 |
| 文章编号： | 1005-281X(2008)06-0984-05 |
| 收稿时间： | 2007-07-05 |
| 修稿时间： | 2007-07-01 |
Scanning Near-field Optical Microscope and Its Applications in the Field of Single Molecules Detection |
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| Hu Mingqian,Cai Jiye. Scanning Near-field Optical Microscope and Its Applications in the Field of Single Molecules Detection[J]. Progress in Chemistry, 2008, 20(6): 984-988 | |
| Authors: | Hu Mingqian Cai Jiye |
| Affiliation: | (Department of Chemistry|College of Life Science and Technology|Jinan University|Guangzhou 510632|China) |
| Abstract: | Scanning near-field optical microscope (SNOM) has unique properties in the field of optical microscope.It breaks through optical diffraction limit , having single molecules detection(SMD) sensitivity without injurying biological samples. This article describes the basic principles of SNOM. Recent advances of SNOM in SMD and applications of SNOM combined with quantum dots(QDs) are introduced. The future prospectives of SMD are also presented. |
| Keywords: | scanning near-field optical microscope (SNOM) single molecule detection(SMD) quantum dots |
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