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Determination of melamine in milk powder using gas chromatography-high-resolution isotope dilution mass spectrometry
Authors:Koh Guiwan  Chia Rosalind S C  Lin Qi  Cheow Pui-Sze  Teo Tang-Lin  Lee Tong-Kooi
Institution:Health Sciences Authority, Chemical Metrology Division, Chemical Metrology Laboratory, The Capricorn, Singapore Science Park II, Singapore.
Abstract:A GC-high-resolution isotope dilution MS (IDMS) method for the quantification of melamine in milk powder is described. The developed technique is compared to the LC-IDMS/MS technique, typically used for the determination of melamine in various matrices. The accuracy of the GC-high-resolution IDMS method was demonstrated when a small degree of equivalence was obtained in a regional comparative study involving the determination of melamine in milk powder.
Keywords:GC  High resolution isotope dilution MS  Melamine  Milk powder
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