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| On-line Separation and Detection of Peptides by Capillary Electrophoresis / Electrospray FT-ICR-MS | |
| 引用本文： | Bin XIN,Dan PU,Shao Xiang XIONG*,Guang Hui WANG Beijing Mass Spectrometry Center,Center for Molecular Science,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100080. On-line Separation and Detection of Peptides by Capillary Electrophoresis / Electrospray FT-ICR-MS[J]. 中国化学快报, 2003, 14(2) |
| 作者姓名： | Bin XIN Dan PU Shao Xiang XIONG* Guang Hui WANG Beijing Mass Spectrometry Center Center for Molecular Science Institute of Chemistry Chinese Academy of Sciences Beijing 100080 |
| 作者单位： | Bin XIN，Dan PU，Shao Xiang XIONG*，Guang Hui WANG Beijing Mass Spectrometry Center，Center for Molecular Science，Institute of Chemistry，Chinese Academy of Sciences，Beijing 100080 |
| 基金项目： | supported by the National Natural Science Foundation of China (20035010 and 20175033) and Instrumental Innovation Project of Chinese Academy of Sciences. |
| 摘 要： | Recently, capillary electrophoresis/electrospray ionization mass spectrometry (CE/ESI- MS) has been rapidly developed as a powerful analytical tool for charged species ranged from small molecules such as carboxylic acids1, phenolic compounds2, metal species3, tetramines4, herbicides5, drugs and drug metabolites6 to peptides and proteins7, 8. The ESI mode has proven to be sensitive, versatile and relatively easy to use in combination with CE. CE confers rapid analysis and efficient separ… |
On-line Separation and Detection of Peptides by Capillary Electrophoresis/Electrospray FT-ICR-MS |
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| Bin XIN,Dan PU,Shao Xiang XIONG,Guang Hui WANG. On-line Separation and Detection of Peptides by Capillary Electrophoresis/Electrospray FT-ICR-MS[J]. Chinese Chemical Letters, 2003, 14(2) | |
| Authors: | Bin XIN Dan PU Shao Xiang XIONG Guang Hui WANG |
| Abstract: | The coupling of capillary electrophoresis to electrospray Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) was presented for the on-line separation and detection of mixture of peptides. With the ultra-high resolution and unmatchable mass measurement accuracy FT-ICR-MS provides, the separation and identification of angiotensin III, octreotide and elastin chemotactic were successfully achieved using this fabricated device, which showed its great application potential in detection and structural identification for multicomponent sample. |
| Keywords: | Capillary electrophoresis FT-ICR-MS peptide. |
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