Inhibitory effects of 3-O-acyl-(+)-catechins on Epstein-Barr virus activation |
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| Authors: | Uesato Shinichi Taniuchi Keisuke Kumagai Ayako Nagaoka Yasuo Seto Ryota Hara Yukihiko Tokuda Harukuni Nishino Hoyoku |
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| Affiliation: | Department of Biotechnology, Faculty of Engineering, Kansai University, Suita, Osaka, Japan. uesato@ipcku.kansai-u.ac.jp |
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| Abstract: | In the course of an exploratory investigation of antitumor-promoting catechins, 3-O-acyl-(+)-catechins of varying carbon lengths from C(4) to C(18) were assessed for inhibitory effects on the activation of the Epstein-Barr virus early antigen. Like 3-O-acyl-(-)-epigallocatechins, the (+)-catechin derivatives showed promising effects with the C-3 acyl chain of C(8)-C(11) carbon atoms. |
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