Efficient highly diastereoselective synthesis of 1,8a-dihydro-7H-imidazo[2,1-b][1,3]oxazines |
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| Authors: | Mehdi Adib Esmaeil Sheibani Khadijeh Ghanbary |
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| Institution: | a Department of Chemistry, Faculty of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran
b Department of Chemistry, Tarbiat Modarres University, Tehran, Iran |
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| Abstract: | 1-Alkyl imidazoles react smoothly with dialkyl acetylenedicarboxylates in the presence of pyridine carboxaldehydes to diastereoselectively produce 1,8a-dihydro-7H-imidazo2,1-b]1,3]oxazine derivatives in excellent yields. |
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| Keywords: | Diastereoselective synthesis Pyridine carboxaldehydes Acetylenic esters 1-Alkyl imidazoles 1 8a-Dihydro-7H-imidazo[2 1-b][1 3]oxazines |
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