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Asymmetric synthesis of homo-apioneplanocin A from d-ribose
Authors:Jin-Hee Kim  Kang Man Lee  Hyung Ryong Moon
Institution:a College of Pharmacy, Seoul National University, Seoul 151-742, Republic of Korea
b Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul 120-750, Republic of Korea
c College of Pharmacy, Pusan National University, Busan 609-753, Republic of Korea
Abstract:Homo-apioneplanocin A was efficiently synthesized via stereoselective hydroxymethylation, regio- and chemoselective hydroboration, and chemoselective oxidation as key steps from d-ribose.
Keywords:Homo-apioneplanocin A  Stereoselective hydroxymethylation  Chemoselective hydroboration  Chemoselective oxidation
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