TVS和CEUS诊断子宫内膜良恶性病变的价值

本次研究的目的是探讨子宫内膜良恶性病变中,经阴道超声检查(TVS)和超声造影(CEUS)的鉴别诊断价值。选取确诊的子宫内膜病变患者108例,给予TVS和CEUS检查。经病理学检查,恶性病变60例,良性病变48例;CEUS诊断子宫内膜良恶性病变的灵敏性、准确性和阴性预测值明显高于TVS检查(P<0.05);恶性病变和良性病变阻力指数(RI)、达峰时间(TTP)与峰值强度(Peak)有明显差异(P<0.05);Ⅲ~Ⅳ和Ⅰ~Ⅱ期RI、TTP和Peak有明显差异(P<0.05);RI、Peak和TTP诊断子宫内膜恶性病变的ROC曲线下面积分别为0.740、0.789和0.856,P<0.05。相比较TVS,CEUS鉴别诊断子宫内膜良恶性疾病有较好的价值,值得临床应用。

The Value of TVS and CEUS in the Diagnosis of Benign and Malignant Endometrial Lesions

The purpose of this study was to explore the value of transvaginal ultrasonography(TVS) and contrast-enhanced ultrasound(CEUS) in the differential diagnosis of endometrial benign and malignant lesions. One-hundred and eight patients with endometriosis were selected, and they were given TVS and CEUS inspection. According to pathological examination, 60 cases were malignant and 48 cases were benign. The sensitivity, accuracy and negative predictive value of CEUS diagnosis of endometrial benign and malignant lesions were significantly higher than those of TVS(P<0.05). The resistance index(RI), time to peak(TTP) and peak intensity(Peak) of malignant lesions and benign lesions were significantly different(P<0.05). The RI, TTP and peak of stage Ⅲ-Ⅳ and Ⅰ-Ⅱ were significantly different(P<0.05). The area under ROC curve of RI, peak and TTP in the diagnosis of endometrial malignant lesions were 0.740, 0.789 and 0.856, P<0.05. Compare with TVS, CEUS has a better value in differential diagnosis of endometrial benign and malignant diseases, which is worth clinical application.