Synthesis of photocleavable poly(methyl methacrylate‐block‐d‐lactide) via atom‐transfer radical polymerization and ring‐opening polymerization |
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| Authors: | Hong Li Sahas Rathi Elizabeth S Sterner Hui Zhao Shaw Ling Hsu Patrick Theato Yongming Zhang E Bryan Coughlin |
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| Institution: | 1. School of Chemistry and Chemical Engineering, Shanghai Jiaotong University, , Shanghai, 200240 People's Republic of China;2. Department of Polymer Science and Engineering, University of Massachusetts Amherst, , Massachusetts, 01003;3. Institute for Technical and Macromolecular Chemistry, University of Hamburg, , Hamburg, D‐20146 Germany |
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| Abstract: | The synthesis and characterization of a photocleavable block copolymer containing an ortho‐nitrobenzyl (ONB) linker between poly(methyl methacrylate) and poly(d ‐lactide) blocks is presented here. The block copolymers were synthesized via atom transfer radical polymerization (ATRP) of MMA followed by ring‐opening polymerization (ROP) of d ‐Lactide and ROP of d ‐lactide followed by ATRP of MMA from a difunctional photoresponsive ONB initiator, respectively. The challenges and limitations during synthesis of the photocleavable block copolymers using the difunctional photoresponsive ONB initiator are discussed. The photocleavage of the copolymers occurs under mild conditions by simple irradiation with 302 nm wavelength UV light (Relative intensity at 7.6 cm: 1500 μW/cm2) for several hours. © 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2013, 51, 4309–4316 |
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| Keywords: | atom transfer radical polymerization (ATRP) block copolymers d‐lactide photochemistry photocleavable photoreactive effects ring‐opening polymerization |
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