Pyrolysis and combustion of tobacco in a cigarette smoking simulator under air and nitrogen atmosphere |
| |
Authors: | Christian?Busch Email author" target="_blank">Thorsten?StreibelEmail author Chuan?Liu Kevin?G?McAdam Ralf?Zimmermann |
| |
Institution: | 1.Joint Mass Spectrometry Centre, Chair of Analytical Chemistry, Institute of Chemistry,University of Rostock,Rostock,Germany;2.Group Research and Development Centre,British American Tobacco,Southampton,UK;3.Joint Mass Spectrometry Centre, Cooperation Group “Analysis of Complex Molecular Systems,” Institute of Ecological Chemistry,Helmholtz Zentrum München–German Research Centre for Environmental Health,Neuherberg,Germany |
| |
Abstract: | A coupling between a cigarette smoking simulator and a time-of-flight mass spectrometer was constructed to allow investigation
of tobacco smoke formation under simulated burning conditions. The cigarette smoking simulator is designed to burn a sample
in close approximation to the conditions experienced by a lit cigarette. The apparatus also permits conditions outside those
of normal cigarette burning to be investigated for mechanistic understanding purposes. It allows control of parameters such
as smouldering and puff temperatures, as well as combustion rate and puffing volume. In this study, the system enabled examination
of the effects of “smoking” a cigarette under a nitrogen atmosphere. Time-of-flight mass spectrometry combined with a soft
ionisation technique is expedient to analyse complex mixtures such as tobacco smoke with a high time resolution. The objective
of the study was to separate pyrolysis from combustion processes to reveal the formation mechanism of several selected toxicants.
A purposely designed adapter, with no measurable dead volume or memory effects, enables the analysis of pyrolysis and combustion
gases from tobacco and tobacco products (e.g. 3R4F reference cigarette) with minimum aging. The combined system demonstrates
clear distinctions between smoke composition found under air and nitrogen smoking atmospheres based on the corresponding mass
spectra and visualisations using principal component analysis. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|