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New Sesquiterpenes from a Taiwanese Marine Sponge of the Genus Parahigginsia |
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| Authors: | Ya-Ching Shen Chin-Yeu Chen Chang-Yin Dun |
| Abstract: | An undescribed Taiwanese marine sponge of the genus Parahigginsia yielded two new sesquiterpene hydrocarbons-parahigginine ( 1 ) and parahigginone ( 2 ). The structures of the new compounds were established on the basis of NMR spectroscopic and mass spectrometric data. Compounds 1 and 2 exhibited moderate cytotoxicity against murine P-388 and human KB-16, A-549, and HT-29 tumor cells. |
| Keywords: | Sponge Parahigginsia sp. Sesquiterpenes Antitumor cytotoxicity |