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A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities
Authors:Wei Ping YIN   Tian Zeng ZHAO   Ling Jie GAO   Da Peng ZOU   Jian Xun KANG
Abstract:A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. itsstructure was determined as 1 6. 2 6. 9 a-triacetoxy-8 a-(a-hydroxyl-isobutyryloxy)-15-benzoyloxy-4 a-hydroxy-dihydroagarofuran by means of NMR. MS and IR spectral analysis.Preliminary biological study on antitumor activity revealed that this compound showed strongnonselective cytotoxicity against four of the NCI panel cell lines.
Keywords:Celastrus angulatus   sesquiterpene polyol ester   NMR. activities activities
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