A Novel Sesquiterpene Polyol Ester from Celastrus Angulatus and its Antitumor Activities |
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Authors: | Wei Ping YIN Tian Zeng ZHAO Ling Jie GAO Da Peng ZOU Jian Xun KANG |
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Abstract: | A new sesquiterpene polyol ester was isolated from the leaves of Celastrus angulatus. itsstructure was determined as 1 6. 2 6. 9 a-triacetoxy-8 a-(a-hydroxyl-isobutyryloxy)-15-benzoyloxy-4 a-hydroxy-dihydroagarofuran by means of NMR. MS and IR spectral analysis.Preliminary biological study on antitumor activity revealed that this compound showed strongnonselective cytotoxicity against four of the NCI panel cell lines. |
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Keywords: | Celastrus angulatus sesquiterpene polyol ester NMR. activities activities |
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