Study of the Reaction between Nucleic Acids and Tb-BPMPHD-CTMAB Complex and its Analytical Application

The direct use of the fluorescence emission properties of nucleic acids in the investigation of their biological properties is limited, whereas the use of metal complexes as fluorescence probe to study nucleic acids has increased remarkbly. Recently we found that the Tb-l,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hezane-dione(BPMPHD)-trimethyl am-monium bromide(CTMAB) complex can be used as a sensitive fluorescence probe for the determination of nucleic acids.