AgNP-decorated SBA-15 for MWCNT Paste Modified Electrode: A Sensor for Simultaneous Voltammetric Determination of Paracetamol and Sulfamethoxazole |
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| Authors: | Oleg S. Tkachenko Luana V. Souza Monique Deon Emilene M. Becker Eliana W. de Menezes Leliz T. Arenas Edilson V. Benvenutti |
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| Affiliation: | 1. Materials Chemistry Department, V. N. Karazin Kharkiv National University, 4 Svoboda Square, Kharkiv, 61022 Ukraine;2. Institute of Chemistry, UFRGS, PO Box 15003, CEP 91501-970 Porto Alegre, RS Brazil |
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| Abstract: | A new electrochemical sensor based on a carbon nanotube paste electrode modified with a Santa Barbara Amorphous material (SBA-15) decorated with silver nanoparticles, namely CNT/SBA/Ag-PE, was developed. It was successfully applied for individual and simultaneous determination of both paracetamol (PC) and sulfamethoxazole (SMZ) medicines. The electrode exhibited a linear dynamic range of 0.12–110 μmol L−1 for paracetamol and 0.06–70 μmol L−1 for sulfamethoxazole, and detection limits of 38 and 19 nmol L−1, respectively. The proposed sensor offered high sensitivity, fast response time and the potential for detecting both drugs simultaneously. The CNT/SBA/Ag-PE enabled the simultaneous determination of PC and SMZ in urine samples with high recovery rates. |
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| Keywords: | silver nanoparticles ordered silica materials carbon nanotube paste electrode medicines determination ionic silsesquioxane |
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