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Solvent-Free Crossed Aldol Condensation of Ketones with Aromatic Aldehydes Mediated by Magnesium Hydrogensulfate
Authors:Peyman Salehi  Mohammad M. Khodaei  Mohammad A. Zolfigol  Afsaneh Keyvan
Affiliation:(1) Department of Phytochemistry, Medicinal Plants Research Institute, Shahid Beheshti University, Tehran, Iran, IR;(2) Department of Chemistry, Razi University, Kermanshah, Iran, IR;(3) Department of Chemistry, College of Science, Bu-Ali Sina University, Hamadan, Iran, IR
Abstract:
Summary.  Crossed aldol condensations of ketones with aromatic aldehydes are carried out efficiently in the presence of magnesium hydrogensulfate under solvent-free conditions in good to excellent yield without the occurrence of any self-condensation. Similar reactions in solution do not proceed satisfactorily. Corresponding authors. E-mail: p-salehi@cc.sbu.ac.ir Received September 20, 2001. Accepted (revised) January 16, 2002
Keywords:.   Aldehydes   Aldol reactions   Ketones   Magnesium hydrogensulfate   Solid state
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