Electrochemical determination of sulfaguanidine using COOH-MWCNT coated GC electrode

The electrochemical behavior of sulfaguanidine was investigated in PBS buffer aqueous solutions. Cyclic voltammograms have shown that (1) the Sg provided a well-defined irreversible oxidation peak (2) the signal-to-background current ratio is 3 times higher at COOH-MWCNT coated GCE than that of bare GCE and (3) the modifying GCE surface by COOH-MWCNT led to a significant improvement (2.7 folds) of the electrochemical response. It has been shown that Sg oxidizes according to a diffusion-controlled mechanism. A linear calibration curve was obtained for the oxidation of Sg at 10–70 μM. The COOH-MWCNT coated GCE has also been successfully used for the determination of Sg in real samples.