| 红外光谱技术在医学中的应用 |
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| 引用本文： | 张小青,徐智,凌晓锋,徐怡庄,吴瑾光.红外光谱技术在医学中的应用[J].光谱学与光谱分析,2010,30(1):30-34. |
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| 作者姓名： | 张小青 徐智 凌晓锋 徐怡庄 吴瑾光 |
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| 作者单位： | 1.北京大学第三医院普通外科，北京 100191
2.北京大学化学与分子工程学院，北京 100871 |
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| 基金项目： | 国家自然科学基金项目(50673005);;北京市自然科学基金项目(2072020)资助 |
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| 摘 要： | 系统回顾了过去50余年中红外光谱技术的发展创新及在生物医学领域中的研究应用。傅里叶变换红外光谱技术已从对单个细胞水平结构构成与形态的研究进展到组织水平。现代红外光谱技术联合成熟的模式识别技术与组织微阵列技术，为平行大规模测定分子结构提供了可能。此外，红外光谱技术的临床应用为良恶性肿瘤的判别提供了可信的参考依据，并可准确判别甲状腺、乳腺、胃肠道及腮腺等组织的良恶性，具有极广泛的应用前景。
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| 关 键 词： | 中红外光谱 生物医学诊断 组织检测 恶性肿瘤 |
| 收稿时间： | 2009-02-16 |
The Application of Fourier Transform Infrared Technology in Biomedical Sphere |
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| ZHANG Xiao-qing,XU Zhi,LING Xiao-feng,XU Yi-zhuang,WU Jin-guang.The Application of Fourier Transform Infrared Technology in Biomedical Sphere[J].Spectroscopy and Spectral Analysis,2010,30(1):30-34. |
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| Authors: | ZHANG Xiao-qing XU Zhi LING Xiao-feng XU Yi-zhuang WU Jin-guang |
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| Institution: | 1.General Surgery, Peking University Third Hospital, Beijing 100191, China2.College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China |
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| Abstract: | The authors systemically reviewed the development of FTIR technology and its innovative advances during the past fifty years.FTIR technique was once abandoned after initial exploration in biomedical fields,which could not confirm its reliability and credibility.After technological innovation and refined numerical analysis methods,FTIR technique has been applied to a wide range of fields,from single cellular to the complex biomedical tissue components.Nowadays,mature and advanced FTIR technology,such as FTIR... |
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| Keywords: | Mid-infrared spectroscopy Biomedical diagnosis Tissue analysis Malignancy |
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