Radiation synthesis and magnetic properties of novel Co0.7Fe0.3/Chitosan compound nanoparticles for targeted drug carrier |
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| Affiliation: | 1. Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA;2. Cardiovascular Division, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA;1. Department of Chemical and Pharmaceutical Engineering, Faculty of Chemistry and Pharmacy, Sofia University, 1164 Sofia, Bulgaria;2. Unilever Research & Development, Port Sunlight, Wirral, Merseyside CH63 3JW, UK;3. Unilever Research & Development Vlaardingen, 3133AT Vlaardingen, The Netherlands;4. Laboratory of Physical Chemistry and Colloid Science, Wageningen University, 6703 HB Wageningen, The Netherlands;5. Department of Mechanical Engineering, University College London, WC1E 7JE, UK;1. Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan;2. Department of Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan |
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| Abstract: | Chitosan coated Co0.7Fe0.3 compound nanoparticles were successfully synthesized through a γ-radiation route in inverse microemulsion system. An observation of transmission electron microscope (TEM) showed that the diameter of these nanoparticles was about 50 nm with narrow size-distribution. Investigations of properties of nanoparticles were also conducted with fourier transform infrared spectrometer (FT-IR), X-ray diffraction (XRD) and energy dispersion spectrum (EDS). Analysis of vibrating sample magnetometer (VSM) indicated that the nanoparticles were superparamagnetic with a saturation magnetization of 24 emu/g. These compound nanoparticles were undertaken to allow for the magnetically targeted cancer. |
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