Discovering new MAP kinase inhibitors |
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| Authors: | Shapiro Paul |
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| Affiliation: | Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Room 536, 20 North Pine Street, Baltimore, MD 21201, USA. |
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| Abstract: | ![]()
The current study by Kim et al. (in this issue of Chemistry & Biology) uses a genetic approach with the yeast Schizosaccharomyces pombe to identify a highly specific inhibitor of Spc1 MAP kinase that competes with protein substrates for Spc1 interactions, but not with ATP binding. |
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