Silica‐supported synthesis of some 1,3,5‐trisubstituted 2‐pyrazolines under solvent‐free and microwave irradiation conditions

A simple method for the synthesis of 2‐pyrazolines is described which occurs on silica surface under solvent‐free conditions within 110‐180 sec using microwave irradiation. The results obtained indicate that the use of silica gel as a support in pyrazoline formation reactions can have a profound effect on reaction rates and yields and cause cleaner reaction conditions.