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Nucleosides XIII. Facile Synthesis of 4‐Amino‐1‐(2‐deoxy‐β‐D‐ribofuranosyl)quinazolin‐2‐one as a 2′‐Deoxycytidine Analog for Oligonucleotide Synthesis |
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| Authors: | Tun‐Cheng Chien Chien‐Shu Chen Ji‐Wang Chern |
| Abstract: | 4‐Amino‐1‐(2‐deoxy‐β‐D‐ribofuranosyl)quinazolin‐2‐one (4) was prepared by Barton deoxygenation from 4‐amino‐1‐(β‐D‐ribofuranosyl)quinazolin‐2‐one (3) as a 2′‐deoxycytidine analog. |
| Keywords: | 2′ ‐Deoxycytidine Cytidine Quinazolinone Barton deoxygenation Markiewicz silylation |