A synthesis of potential new antiarrhythmic agents

N‐Ethylation of substituted ethyl 1H‐indole‐2‐carboxylates with iodoethane and potassium carbonate gave substituted ethyl 1‐ethyl‐1H‐indole‐2‐carboxylates. The later compounds on treatment with a range of aryl amines with varying structural complexity, gave the desired ethyl 1H‐indole‐2‐carboxamide analogues.