Synthesis of one‐, two‐ and three‐ring macrocyclic,bifunctional compounds for use in radiolabelling monoclonal antibodies |
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Authors: | Martalena Rami Ying Dong Leonard F. Lindoy Suzanne V. Smith J.Gerald Wilson |
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Abstract: | The synthesis of new linked bis‐ and tris‐ring tetraazamacrocyclic (bifunctional) reagents for use in an alternative strategy for radiolabelling antibodies is described. For comparison with the above systems, a new single ring bifunctional system incorporating a dioxocyclam ring is also reported. |
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