Copper-catalyzed N-arylation of amines with part-per-million catalyst loadings under air at room temperature |
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| Authors: | Xie Ruilong Fu Hua Ling Yun |
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| Affiliation: | Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, PR China. |
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| Abstract: | An efficient copper-catalyzed method for N-arylation of amines has been developed with part-per-million catalyst loadings at room temperature under air. Reactions of substituted (E)-1-(2-halophenyl)alkanone oximes with aliphatic amines or aromatic amines provided the N-arylation products in good to excellent yields. |
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