Visible-light promoted synthesis of 3-arylthioindoles from indoles and diaryl disulfides |
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| Authors: | Lin-miao Ye Jie Chen Peng Mao Xue-jing Zhang Ming Yan |
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| Institution: | Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China |
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| Abstract: | 3-Arylthioindoles could be synthesized in good yields via the photoirradiation of indoles and disulfides. The reaction is efficiently promoted by the catalytic amount of sodium iodide. A reaction mechanism involving the electrophilic substitution of indoles with arylsulfenyl iodine intermediates is suggested. |
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| Keywords: | Photoirradiation Synthesis 3-Arylthioindole Disulfide |
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