1. Department of Natural Product Chemistry, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500007, India;2. Academy of Scientific and Innovative Research (AcSIR), New Delhi, India
Abstract:
A simple, mild, and ecofriendly protocol for a palladium-catalysed direct arylation of imidazo[1,2-a]pyridines with aryl halides on water is reported. This protocol does not require any ligand and tolerate variety of functional groups on both the coupling partners. The simple base KOH is highly efficient in this transformation.
