Hydroxyl ammonium ionic liquid-catalyzed simple and efficient synthesis of 5-arylidene-2,4-thiazolidinediones under solvent-free conditions |
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| Authors: | Jun Zhang Yuliang Zhang |
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| Institution: | Key Laboratory of Catalysis and Materials Science of the State Ethnic Affairs Commission and Ministry of Education, College of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan, China |
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| Abstract: | A simple and efficient synthesis of 5-arylidene-2,4-thiazolidinediones by the Knoevenagel condensation of aldehydes with 2,4-thiazolidinedione in the presence of 2-hydroxy ethylammonium propionate under solvent-free conditions is described. The attractive features of this procedure are operational simplicity, high yields, short reaction times, easy to prepare the catalyst, mild and environmentally benign reaction conditions, and recycle of the catalyst. |
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| Keywords: | 5-arylidene-2 4-thiazolidinedione Knoevenagel condensation solvent-free conditions 2-hydroxy ethylammonium propionate |
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