| ADSORBENTS USED IN THE CLEARANCE OF ENDOTOXIN |
| |
| 引用本文： | YU Mei LIU Tao Hou Guanghui[( )-241.4( )]YUAN Zhi** State Key Laboratory of Functional Polymer Materials for Adsorption and Separation Institute of Polymer Chemistry,Nankai University,Tianjin 300071,China. ADSORBENTS USED IN THE CLEARANCE OF ENDOTOXIN[J]. Chinese Journal of Reactive Polymers, 2003, 0(1) |
| |
| 作者姓名： | YU Mei LIU Tao Hou Guanghui[( )-241.4( )]YUAN Zhi** State Key Laboratory of Functional Polymer Materials for Adsorption and Separation Institute of Polymer Chemistry Nankai University Tianjin 300071 China |
| |
| 作者单位： | YU Mei LIU Tao Hou Guanghui[( )-241.4( )]YUAN Zhi** State Key Laboratory of Functional Polymer Materials for Adsorption and Separation Institute of Polymer Chemistry，Nankai University，Tianjin 300071，China |
| |
| 基金项目： | “973”(G1999064707)(973)，Trans-Century Training Programme Foundation for the Talents and Nature Science Foundation of Tianjin (013614011). |
| |
| 摘 要： | 1.INTRODUCTION[()-227.3()]Endotoxinislipopolysaccharide(LPS)derivedfromthecellmembranesofgram-negativebacteria.Endotoxincancausefebrilereactionsinanimalswithsymptomsofhighfever,vasodilation,diarrheaandfetalshockwheninjectedeveninaverysmallamount[1].Iftheconcentrationofendotoxininpatients?bloodishighenoughitcancauseseveresepsis,whichisamajorcauseofdeathinpatientsandcontinuestohaveahighmortalitydespiteappropriatesurgery,potentantibiotic,andintensivesupportivetherapy[2~5].LipidAisthemaintox…
|
ADSORBENTS USED IN THE CLEARANCE OF ENDOTOXIN |
| |
| YU Mei LIU Tao Hou Guanghui[. ADSORBENTS USED IN THE CLEARANCE OF ENDOTOXIN[J]. 离子交换与吸附(英文版), 2003, 0(1) |
| |
| Authors: | YU Mei LIU Tao Hou Guanghui[ |
| |
| Abstract: | A series of modified poly (methyl methacrylate, PMMA) resins were prepared and compared their adsorption abilities to endotoxin. The results showed that adsorbents, which were grafted with tertiary amine and long spacing arms, had the best adsorption capacities and good blood compatibility. It is hopeful to be used as adsorbent in hemoperfusion for clinical clearance of endotoxin. The influence of original concentration of endotoxin on adsorption and the adsorption mechanism were also investigated. |
| |
| Keywords: | Endotoxin adsorption adsorbent hemoperfusion |
| 本文献已被 CNKI 等数据库收录！ |
