New synthesis of enantiomerically pure (S)-3-amino-2-phenyl propanoic acid via the asymmetric transformation of its racemic N-phthaloyl derivative |
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Affiliation: | 1. Faculty of Chemistry, University of Wrocław, F. Joliot-Curie 14, 50-383 Wrocław, Poland;2. Department of Chemistry, Taras Shevchenko National University of Kyiv, Volodymyrska Street, 64/13, Kyiv 01601, Ukraine;1. Department of Chemistry, Aligarh Muslim University, Aligarh, 202002, India;2. Recombinant Gene Products Group, International Centre for Genetic Engineering & Biotechnology (ICGEB), New Delhi, 110067, India |
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Abstract: | The synthesis of racemic N-phthalyl 3-amino-2-phenyl propanoic acid and its asymmetric transformation via the corresponding prochiral ketene have been investigated, allowing the preparation of enantiomerically pure (S)-3-amino-2-phenyl propanoic acid. |
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