Volatile profiling reveals intracellular metabolic changes in <Emphasis Type="Italic">Aspergillus parasiticus</Emphasis>: <Emphasis Type="Italic">veA</Emphasis> regulates branched chain amino acid and ethanol metabolism |
| |
| Authors: | Ludmila V Roze Anindya Chanda Maris Laivenieks Randolph M Beaudry Katherine A Artymovich Anna V Koptina Deena W Awad Dina Valeeva Arthur D Jones John E Linz |
| |
| Institution: | (1) Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, USA;(2) Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, USA;(3) Department of Horticulture, Michigan State University, East Lansing, MI, USA;(4) Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA;(5) Department of Chemistry, Michigan State University, East Lansing, MI, USA;(6) National Food Safety and Toxicology Center, Michigan State University, East Lansing, MI, USA |
| |
| Abstract: | Background Filamentous fungi in the genus Aspergillus produce a variety of natural products, including aflatoxin, the most potent naturally occurring carcinogen known. Aflatoxin
biosynthesis, one of the most highly characterized secondary metabolic pathways, offers a model system to study secondary
metabolism in eukaryotes. To control or customize biosynthesis of natural products we must understand how secondary metabolism
integrates into the overall cellular metabolic network. By applying a metabolomics approach we analyzed volatile compounds
synthesized by Aspergillus parasiticus in an attempt to define the association of secondary metabolism with other metabolic and cellular processes. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
