Microwave‐Assisted Convenient Synthesis of α,β‐Unsaturated Esters and Ketones via Aldol‐Adduct Elimination |
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| Authors: | Pathi Suman Rayala Nageswara?Rao Bhimapaka China?Raju |
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| Institution: | 1. Natural Products Chemistry Division, CSIR‐Indian Institute of Chemical Technology, Hyderabad‐500 007, India, (phone: +914027191725;2. fax: +91402716512) |
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| Abstract: | Various fluorinated 3‐oxo ester/1,3‐diketones were reacted with carbonyl compounds, in presence of piperidine and under microwave irradiation, to afford (E)‐α,β‐unsaturated esters and ketones in good yields. The systematic study reveals that the reaction proceeded through the formation of aldol adduct. The method provides a new and simple way for C,C bond formations. |
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| Keywords: | Aldol‐adduct elimination C C‐Bond formation Microwave irradiation Ketones Esters Fluorine compounds 1 3‐Diketones |
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