High‐Selective Tramadol Sensor Based on Modified Molecularly Imprinted Polymer?Carbon Paste Electrode with Multiwalled Carbon Nanotubes |
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| Authors: | Majid Soleimani Majid Ghahraman Afshar Atefeh Shafaat Gastón A Crespo |
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| Institution: | 1. Department of Chemistry, Imam Khomeini International University (IKIU), P.?O. Box 288, Qazvin, Iran;2. Department of Inorganic and Analytical Chemistry, Quai E.‐Ansermet 30, University of Geneva, 1211 Geneva 4, Switzerland |
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| Abstract: | We report here a novel carbon paste electrode (CPE) which is able to quantitatively sense tramadol under physiological conditions without sample preparation step. The selectivity of CPE is modified by applying molecularly imprinted polymer (MIP) technology. Multiwalled carbon nanotubes (MWCNTs) are incorporated in the structure of CPE to improve the conductivity and the ion‐to‐electron transduction. The electrode shows a wide dynamic linear range for tramadol from 10?7 to 10?3 M. The observed limit of detection and % RSD are 5×10?7 M and 1.8 %, respectively. Finally, the proposed method is applied to determine tramadol in urine and medicinal tablets. |
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| Keywords: | Tramadol Molecularly imprinted polymers Carbon paste electrodes Multiwalled carbon nanotubes |
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