分子印迹-电化学发光技术研究进展

分子印迹-电化学发光技术具有分子印迹技术的高选择性及电化学发光技术的高灵敏性,以及发光易于调控、稳定性好、便于微型化和仪器操作简单等优点,已被广泛地应用于重金属检测、免疫传感技术、基因传感技术、酶传感技术、食品安全与药物分析等领域。该文结合本实验室的研究工作介绍了分子印迹电化学发光传感器的原理和构建思路。在此基础上,着重介绍了分子印迹电化学发光技术在食品安全与药物分析中的应用,并对其今后的研究趋势进行了展望。

Recent Advances in Molecular Imprinting-Electrochemiluminescence Technology

Molecularly imprinted electrochemiluminescence sensors combine the specific recognition ability and predetermined selectivity properties of molecularly imprinted polymer with the high sensitivity of electrochemiluminescence technology.In addition,these sensors exhibited a high maneuverability for luminescence signal from the reactions with good reproducibility,long-term stability and easy operation,which have received a great deal of attention in applications of pharmaceutical analysis,heavy metal ion detection,immune biosensors,gene biosensos,enzymatic biosensors,toxic pesticide residue detection and food safety monitoring.The preparation mechanism and construction thinking of the sensors are summaried in this review.Moreover,the applications on food safety and drugs detection of molecular imprinted polymer electrochemiluminescence sensors are highlighted,and the development trend of molecular imprinted polymer electrochemiluminescence sensors is revealed.