海藻酸钠-硫酸软骨素共混膜的结构及性能研究

利用溶液共混法成功制备了新型生物膜材料-硫酸软骨素共混膜,通过红外光谱、X-射线衍射、原子吸收光谱和扫描电镜对共混膜的结构进行了表征,并测定了不同配比共混膜的抗张强度、断裂伸长率,吸水率,同时考察了介质pH值和离子强度对共混膜吸水率的影响。结果表明:共混膜中海藻酸钠、软骨素之间具有较强的相互作用和良好的相容性,共混膜具有良好的力学性能。作为一种潜在的生物材料可望在生物医学领域得到应用。

Study on structure and properties of sodium alginate-chondroitin sulfate blend films

Sodium alginate/ chondroitin sulfate blend films were prepared successfully by solution method. The structure of the blend film was characterized by FT-IR, XRD, atomic absorption spectrophotometer and SEM, respectively. The effects of weight ratio between the two polymers on tensile strength, elongation at break and water absorption of the blend films were studied,respectively. The effects of weight ratio between the two polymers on tensile strength, elongation at break, water permeability and water absorption of the blend films were measured. Meanwhile, The effect of NaCl concentration and pH value on water absorption of the blend film was studied. The results showed that there were strong interactions and good compatibility between sodium alginate and chondroitin sulfate in the blend films. The blend films possessed good mechanical property. Therefore, they can be applied in biomedicine as a new type of biomaterial.