Ascomycotin A,a new citromycetin analogue produced by Ascomycota sp. Ind19F07 isolated from deep sea sediment |
| |
| Authors: | Yong-qi Tian Xiu-ping Lin Juan Liu Kumaravel Kaliyaperumal Wen Ai Zhi-ran Ju |
| |
| Institution: | 1. Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, P.R. China;2. University of Chinese Academy of Sciences, Beijing 100049, P.R. China |
| |
| Abstract: | A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( ? )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the fungal strain Ascomycota sp. Ind19F07, which was isolated from the deep sea sediment of the Indian Ocean. The structures of the compounds were established by spectroscopic data including 1D and 2D NMR and HR-ESI-MS. Compounds (1–9) were evaluated for antibacterial activity. |
| |
| Keywords: | fungi deep sea sediment citromycetin analogue spectroscopy |
|
|
