A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp. |
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| Authors: | Wei Li Xueqiong Yang Yabin Yang Shaohuan Qin Qiling Li Lixing Zhao |
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| Institution: | 1. School of Chemical Science and Technology, Yunnan University, Kunming 650091, P.R. China;2. Yunnan Institute of Microbiology, Yunnan University, Kunming 650091, P.R. China |
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| Abstract: | Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5′-O-acetyl-2′-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (5), 4′,5,6-trihydroxy-7-methoxyisoflavone (6), 2,4,4′-trihydroxy-deoxybenzoin (7), methyl 4-hydroxyphenyl]acetate (8) and daidzein by extensive spectroscopic analyses. Compound 1 was isolated from natural resources for the first time. The antimicrobial and antioxidant activities of compounds 1–8 were investigated. |
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| Keywords: | Nocardia sp antibacterial metabolites endophyte |
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