| Absorption Complex between Porphyrin and Phenothiazine in Reverse Micelles |
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| 作者姓名： | Jun Hua YU Xue Song WANG Bao Wen ZHANG* Yi CAO Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing |
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| 作者单位： | Jun Hua YU，Xue Song WANG，Bao Wen ZHANG*，Yi CAO Technical Institute of Physics and Chemistry，Chinese Academy of Sciences，Beijing 100101 |
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| 摘 要： | Porphyrin derivatives attract much more interest in photodynamic therapy (PDT). Their importance as therapeutic drugs and targeting agents has been widely recognized1, and many of the efforts have been put towards crafting new porphyrin-based molecular entities to achieve enhanced tumor localization, better tissue penetration and increased singlet oxygen quantum yield2. The states of porphyrins in tissue models such as micelles, lipid bilayers are extensively investigated focusing more or l…
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Absorption Complex between Porphyrin and Phenothiazine in Reverse Micelles |
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| Jun Hua YU,Xue Song WANG,Bao Wen ZHANG*,Yi CAO Technical Institute of Physics and Chemistry,Chinese Academy of Sciences,Beijing .Absorption Complex between Porphyrin and Phenothiazine in Reverse Micelles[J].Chinese Chemical Letters,2002,13(10). |
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| Authors: | Jun Hua YU Xue Song WANG Bao Wen ZHANG Yi CAO |
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| Institution: | Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101 |
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| Abstract: | The interaction between amphiphilic porphyrin and phenothiazine in AOT/isooctane/ water reverse micelle was investigated by UV-Vis spectra. A new absorption complex between the two species is formed in such circumstances, which is ascribed to the enrichment of the components by the reverse micelle. The fluorescence quenching of CHTTP by PTH becomes more efficient after the formation of the absorption complex. |
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| Keywords: | Porphyrin phenothiazine absorption complex reverse micelle |
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