气相法分析3-氯-2-羟丙基三甲基氯化铵中的微量有机杂质

 以氯仿为萃取剂 ,对 3 氯 2 羟丙基三甲基氯化铵 (CHPTMA)水溶液进行萃取 ,用气相法分析了CHPT MA溶液中的微量有机杂质环氧氯丙烷和 1 3 二氯丙醇。柱为 2m× 3mmi d 的不锈钢填充柱 ,固定相为10 %的PEG 2 0M ,载体为ChromosorbW/AW。环氧氯丙烷和 1,3 二氯丙醇的回收率分别为 97 5 %～ 10 5 0 %和93 3%～ 98 8% ,相对标准偏差分别为 11 5 %和 13 1% ,最低检测限分别为 5 0 μg/g和 10 0 μg/ g。

Gas Chromatographic Determination of Micro Organic Impurities in 3-Chloro-2-Hydroxypropyl Trimethyl Ammonium Chloride

A simple, rapid and reliable method for the determination of micro organic impurities, epichlorohydrin and 1,3-dichloropropanol, in 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CHPTMA) by gas chromatography is reported. 2-Ethylhexanol was the internal standard. Epichlorohydrin and 1,3-dichloropropanol in CHPTMA were extracted by chloroform. The gas chromatographic separation was achieved on a stainless steel column packed with 10% PEG 20M/Chromosorb W/AW and with a flame ionization detector. The ranges of recovery were 97.5%-105.0% and 93.3%-98.8%, the RSDs were 11.5% and 13.1% and the mininum detectable concentrations were 5.0 micrograms/g and 10 micrograms/g for epichlorohydrin and 1,3-dichloropropanol respectively.