自由基三氟甲基化反应进展

近年来，三氟甲基化反应得到了快速的发展和广泛的关注，由于三氟甲基本身的一些特殊化学和物理性质，使得其在医药、农药和材料等领域发挥着越来越重要的作用。 随着有机氟化学的发展，对于自由基三氟甲基化反应也有了新的认识。 本文通过对不同的三氟甲基试剂作为三氟甲基自由基的前体，综述了近年来自由基三氟甲基化反应的研究进展，并予以展望。

Recent Advances in Radical Trifluoromethylation Reactions

In recent years, research on trifluoromethylation reactions have been developed rapidly. Since the special chemical and physical properties of the trifluoromethyl group, it plays an increasingly important role in the fields of medicine, pesticides and materials. Astheresult, a new recognition of radical trifluoromethylation has been achieved along with the development of organofluorine chemistry. This article delivered an overview of the recent progress of radical trifluoromethylation from the perspective of various radical trifluoromethylative precursors as well as reaction mechanisms.