Sesquiterpene lactones from Saussurea alata |
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| Authors: | Ren G Yu Z M Chen Y L Wu S H Fu C X |
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| Institution: | Research Centre of Siyuan Natural Pharmacy and Bio-toxicity, College of Life Sciences, Zhejiang University, Hangzhou 310058, China. |
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| Abstract: | Two new guaianolides, namely, 3beta,8alpha-dihydroxy-13-methoxyl-4(14),10(15)-dien-(1alphaH,5alphaH,6beta H,11betaH)-12,6-olide (1) and 3beta,8alpha-dihydroxy-13-methoxyl-4(14),10(15)-dien-(1alphaH,5alphaH,6beta H,11alphaH)-12,6-olide (2), together with six known guaianolides, 8-hydroxyzaluzanin C, austricin, chlorojanerin, cynaropicrin, chlorohyssopifolin E and chlorohyssopifolin A were isolated from the aerial parts of Saussurea alata. The structures were established mainly based on spectral analysis, especially 2D NMR techniques. |
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