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The clemmensen reaction of tigogenin. A reinvestigation
Authors:Miguel Zachis  Jaime A. Rabi
Affiliation:Núcleo de Pesquisas de Produtos Naturais, Centro de Ciências da Saúde, Bloco H, Universidade Federal do Rio de Janeiro, Ilha do Fundão, Rio de Janeiro, Brasil
Abstract:The reaction of tigogenin (1b) with amalgamated zinc yields tetrahydrotigogenin (2b) and the furostan 3. While 2b undergoes acid catalyzed elimination to give the rearranged product 7, 3 spontaneously decomposes to a mixture of 4 and 5.
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