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Synthesis of 2H‐Indazolo[2,1‐b]Phthalazine‐1,6,11(13H)‐Trione Derivatives Using Wet Cyanuric Chloride under Solvent‐Free Condition
Authors:Xiao Wang  Wei‐Wei Ma  Li‐Qiang Wu  Fu‐Lin Yan
Institution:School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan 453003, P. R. China
Abstract:A simple and facile synthesis of 2H‐indazolo2,1‐b]phthalazine‐1,6,11(13H)‐trione derivatives has been accomplished by a three‐component condensation reaction of dimedone, aromatic aldehydes and phthalhydrazide under solvent‐free conditions in the presence of wet cyanuric chloride as a catalyst.
Keywords:2H‐Indazolo[2  1‐b]phthalazine‐1  6  11(13H)‐trione  Dimedone  Phthalhydrazide  Cyanuric chloride  Solvent‐free  Multicomponent reation
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