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Enantioselective Allylic Amination of Morita‐Baylis‐Hillman Acetates Catalyzed by Chiral Thiourea‐Phosphine |
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| Authors: | Xuan Zhao Tianchen Kang Jie Shen Feng Sha Xinyan Wu |
| Institution: | Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, China |
| Abstract: | The enantioselective allylic amination of Morita‐Baylis‐Hillman acetates catalyzed by chiral cyclohexane‐based thiourea‐phosphine catalysts was investigated. In the presence of 20 mol% rosin‐derived thiourea‐phosphine 3j , the chiral amines were obtained in up to 88% yield and up to 85% ee. |
| Keywords: | allylic amination chiral phosphine enantioselective organocatalysis Morita‐Baylis‐Hillman acetate phthalimide |