Selective association of cholesterol with long-chain phospholipids in liquid-ordered bilayers: support for the existence of lipid rafts |
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| Authors: | Sugahara Michihiro Uragami Maki Regen Steven L |
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| Affiliation: | Department of Chemistry, Lehigh University, Bethlehem, PA 18015, USA. |
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| Abstract: | ![]()
Nearest-neighbor recognition experiments, which have been carried out under fluidizing and condensing conditions, using exchangeable dimers derived from 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine, and cholesterol, have provided strong evidence that sterol-phospholipid recognition is limited to the liquid-ordered phase. |
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