X-ray investigation of the role of the mixed emulsifier in the structure formation in o/w creams |
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Authors: | Magdolna Kónya Imre Dékány István Erõs |
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Institution: | 1.Department of Pharmaceutical Technology,University of Szeged,Szeged,Hungary;2.Department of Colloid Chemistry,University of Szeged,Szeged,Hungary;3.Budapest,Hungary |
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Abstract: | The aim of this research work was to clarify the role of the mixed emulsifier in the structure formation and water binding
mode in the case of o/w creams prepared with different surfactants. The swelling behavior of mixed emulsifiers was examined
by means of direct investigation methods such as transmission electron microscopy (TEM) and X-ray diffraction. The detailed
structure image of the creams was created with the help of the latter. The influence of the structure of the hydrophilic gel
phase, and the structural changes during storage were studied with rheological methods. On the basis of the results, it can
be stated that the investigated creams had different structures from those mentioned in the literature: surfactant did not
create a mixed bilayer with the structure to furnish fatty amphiphile; instead, micelles were formed. These results correlated
well with the results of the rheological tests. |
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Keywords: | O/w creams Microstructure Mixed emulsifier X-ray diffraction Rheology |
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