Synthetic profile of thiadiazoloquinazolines |
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| Authors: | Bakr F. Abdel-Wahab Abdelbasset A. Farahat |
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| Affiliation: | 1. Applied Organic Chemistry Department, National Research Centre, Dokki, Giza, Egypt;2. Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt |
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| Abstract: | According to the biological screening reports, a thiadiazoloquinazoline scaffold constitutes a promising source of inspiration for the synthesis of novel bioactive molecules. The current review article summarizes the most recent synthetic routes toward thiadiazoloquinazoline derivatives. According to the position of fusion between the thiadiazole and quinazoline rings, thiadiazoloquinazoline derivatives are classified into three major types, thiadiazolo[2,3-b]quinazolines, thiadiazolo[3,2-a]quinazolines and thiadiazolo[3,2-c]quinazolines. |
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| Keywords: | Thiadiazole quinazoline thiadiazolo[3,2-a]quinazoline thiadiazolo[3,2-b]quinazolin thiadiazolo[3,2-c]quinazoline |
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