Isolation and Characterization of Antimicrobial Polypeptide from Loach |
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作者姓名: | Xian Zhi DONG Hui Bi Xu 等 |
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作者单位: | DepartmentofChemistry,HuazhongUniversityofScienceandTechnlogy,Wuhan430074 |
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摘 要: | A novel antimicrobial polypeptide was isoated and characterized from loach,misgurnus anguillicaudatus.The polypeptide,named MAPP,is a single-chain polypeptide with Mw adout 9,800 Dalton and pI about 4.78:the N-tag of MAPP was CFGWN.MAPP showed good inhibition against various bacteria including Bacillus subtilis.Escherichia coli and Staphylococcus aureus.MAPP could be used as a lead compound in antibiotics drug discovery.
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关 键 词: | 多肽 抗菌活性 生物活性 MAPP 分离 结构表征 泥鳅 |
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