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Isolation and Characterization of Antimicrobial Polypeptide from Loach
作者姓名:Xian Zhi DONG Hui Bi Xu 等
作者单位:DepartmentofChemistry,HuazhongUniversityofScienceandTechnlogy,Wuhan430074
摘    要:A novel antimicrobial polypeptide was isoated and characterized from loach,misgurnus anguillicaudatus.The polypeptide,named MAPP,is a single-chain polypeptide with Mw adout 9,800 Dalton and pI about 4.78:the N-tag of MAPP was CFGWN.MAPP showed good inhibition against various bacteria including Bacillus subtilis.Escherichia coli and Staphylococcus aureus.MAPP could be used as a lead compound in antibiotics drug discovery.

关 键 词:多肽 抗菌活性 生物活性 MAPP 分离 结构表征 泥鳅
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