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Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes
Authors:Zhu Zece  Yang Chuluo  Zhou Xiang  Qin Jingui
Institution:Department of Chemistry, Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, Wuhan University, Wuhan 430072, P. R. China.
Abstract:The nucleic acid minor groove binding dyes, DAPI and Hoechst 33258, were for the first time used in label-free aptamer-based sensors for L-argininamide. The synergy binding effect results in the enhancement of fluorescence of dyes. The method for detection of L-argininamide is simple, rapid and cost-effective.
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