| Two new eupodienone lignans from Gymnotheca chinensis |
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| 作者姓名： | Shi-Ji Xiao Fang Chen Li-Sheng Ding Yan Zhou |
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| 作者单位： | a Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China;
b College of Life Science, Sichuan University, Chengdu 610064, China |
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| 基金项目： | financially supported by the grant from the National Natural Sciences Foundation of China (No. 30973634) |
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| 摘 要： | Two new eupodienone lignans, named gymnothelignan T(1) and gymnothelignan U(2) were isolated from the whole plants of endemicmedicinal plant of Gymnotheca chinensis(Saururaceae). The structures of the new compounds were elucidated by means of HRMS, 1D and 2D NMR. Compound 1 was tested for cytotoxic activity in HCT15, HCT116, A549, MCF-7 and HepG2 cells and exhibited no appreciable activity against these tested cell lines with IC50 values above 50 mmol/L.
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| 关 键 词： | Gymnotheca chinensis Saururaceae Eupodienone Lignan |
| 收稿时间： | 8 October 2013 |
Two new eupodienone lignans from Gymnotheca chinensis |
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| Shi-Ji Xiao,Fang Chen,Li-Sheng Ding,Yan Zhou.Two new eupodienone lignans from Gymnotheca chinensis[J].Chinese Chemical Letters,2014,25(3):463-464. |
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| Authors: | Shi-Ji Xiao Fang Chen Li-Sheng Ding Yan Zhou |
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| Institution: | a Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China;
b College of Life Science, Sichuan University, Chengdu 610064, China |
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| Abstract: | Two new eupodienone lignans, named gymnothelignan T(1) and gymnothelignan U(2) were isolated from the whole plants of endemicmedicinal plant of Gymnotheca chinensis(Saururaceae). The structures of the new compounds were elucidated by means of HRMS, 1D and 2D NMR. Compound 1 was tested for cytotoxic activity in HCT15, HCT116, A549, MCF-7 and HepG2 cells and exhibited no appreciable activity against these tested cell lines with IC50 values above 50 mmol/L. |
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| Keywords: | Gymnotheca chinensisSaururaceaeEupodienoneLignan |
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