| Design and Synthesis of Muramyl Dipeptide Cyclic Analogue |
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| 引用本文： | SuoDeZHANG GangLIU 等. Design and Synthesis of Muramyl Dipeptide Cyclic Analogue[J]. 中国化学快报, 2002, 13(1): 17-18 |
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| 作者姓名： | SuoDeZHANG GangLIU 等 |
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| 作者单位： | [1]BeijingInstituteofPharmacologyandToxicology,Beijing,100850 [2]InstituteofMateriaMedica,ChineseAcademyofMedicalSciencesandPekingUnionMedicalCollege,Beijing100050 |
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| 摘 要： | A new conformationalloy restricted cyclic analogue of muramyl dipeptide was designed and manually synthesized by our “Meshed-Bag Gathered-Bunch” method with a combination of Fmoc,ally and N-1-(4,4-dimethyl-2,6-dioxocyclo-hexylidene) ethyl chemical protection strategy.
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| 关 键 词： | 二肽 缩二氨酸 固相合成 循环类似物 缩氨酸 |
Design and Synthesis of Muramyl Dipeptide Cyclic Analogue |
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| Suo De ZHANG,Gang LIU,Su Quan XIA,Ping WU. Design and Synthesis of Muramyl Dipeptide Cyclic Analogue[J]. Chinese Chemical Letters, 2002, 13(1): 17-18 |
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| Authors: | Suo De ZHANG Gang LIU Su Quan XIA Ping WU |
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| Abstract: | A new conformationally restricted cyclic analogue of muramyl dipeptide was designed and manually synthesized by our "Meshed-Bag Gathered-Bunch" method with a combination of Fmoc, allyl and N-1-(4,4-dimethyl-2,6-dioxocyclo-hexylidene)ethyl chemical protection strategy. |
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| Keywords: | Muramyl dipeptide " Meshed-Bag Gathered-Bunch" method cyclic peptides solid- phase synthesis |
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