| 磺化碳催化Biginelli反应一锅法合成3,4-二氢-2(1H)-酮和硫酮(英文) |
| |
| 作者姓名： | Maryam MOGHADDAS Abolghasem DAVOODNIA Majid M.HERAVI Niloofar TAVAKOLI-HOSEINI |
| |
| 作者单位： | Department of Chemistry,Mashhad Branch,Islamic Azad University;Department of Chemistry,School of Sciences,Alzahra University |
| |
| 基金项目： | supported by Islamic Azad University,Mashhad Branch |
| |
| 摘 要： | A sulfonated carbon material was shown to be a highly efficient,eco-friendly,and recyclable solid acid catalyst for the Biginelli reaction of β-ketoester,aldehyde,and urea or thiourea under solvent-free conditions.It gave 3,4-dihydropyrimidin-2(1H)-ones and-thiones in good to excellent yields.This method has the advantages of a simple procedure with easy work-up,short reaction time,and high yields.The catalyst can be recycled after a simple work-up and was reused four times without substantial reduction in activity.
|
| 关 键 词： | sulfonated carbon solid acid Biginelli reaction heterogeneous catalysis solvent-free condition |
Sulfonated Carbon Catalyzed Biginelli Reaction for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and-thiones |
| |
| Maryam MOGHADDAS,Abolghasem DAVOODNIA,Majid M.HERAVI,Niloofar TAVAKOLI-HOSEINI.Sulfonated Carbon Catalyzed Biginelli Reaction for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones and-thiones[J].Chinese Journal of Catalysis,2012,33(4):706-710. |
| |
| Authors: | Maryam MOGHADDAS Abolghasem DAVOODNIA Majid MHERAVI NiloofarTAVAKOLI-HOSEINI |
| |
| Institution: | 1. Department of Chemistry, Mashhad Branch, Islamic Azad University, Mashhad, Iran
2. Department of Chemistry, School of Sciences, Alzahra University, Vanak, Tehran, Iran |
| |
| Abstract: | A sulfonated carbon material was shown to be a highly efficient,eco-friendly,and recyclable solid acid catalyst for the Biginelli reaction of β-ketoester,aldehyde,and urea or thiourea under solvent-free conditions.It gave 3,4-dihydropyrimidin-2(1H)-ones and-thiones in good to excellent yields.This method has the advantages of a simple procedure with easy work-up,short reaction time,and high yields.The catalyst can be recycled after a simple work-up and was reused four times without substantial reduction in activity. |
| |
| Keywords: | sulfonated carbon solid acid Biginelli reaction heterogeneous catalysis solvent-free condition |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
